EvoReproMed Lab

The Evolution, Reproduction and Medicine (EvoReproMed) Lab aims to better understand human infertility by studying the diversity of reproductive mechanisms found in natural  environments. Thus, the lab’s research program can be assigned to a conceptually broad intersection between the fields of environmental health and evolutionary medicine, with a strong focus on the use of comparative biology approaches.

The EvoReproMed Lab believes that collaborative, open science is a powerful engine for the advancement of our understanding of complex diseases such as infertility. Accordingly, the lab collaborates with several top-level Institutions such as the University of Münster (Germany), University at Buffalo (USA), and Nanyang Technical University (Singapore), among others. The lab is also involved in defining and evaluating best practice in the genetic testing of male infertility, in partnership with the European Molecular Genetics Quality Network.

Recent publications:

Brattig-Correia, R., Almeida, J. M., Wyrwoll, M. J., Julca, I., Sobral, D., Misra, C. S., Di Persio, S., Guilgur, L. G., Schuppe, H.-C., Silva, N., Becker, J. D., & Navarro-Costa, P. (2024). The conserved genetic program of male germ cells uncovers ancient regulators of human spermatogenesis. eLife, 13. https://doi.org/10.7554/eLife.95774

Bowman, J. D., Silva, N., Schüftan, E., Almeida, J. M., Brattig-Correia, R., Oliveira, R. A., Tüttelmann, F., Enard, D., Navarro-Costa, P., & Lynch, V. J. (2024). Pervasive relaxed selection on spermatogenesis genes coincident with the evolution of polygyny in gorillas. eLife, 13. https://doi.org/10.7554/ELIFE.94563.1

Lab website.

PNC2

Head: Paulo Navarro-Costa