Environment and Infectious Diseases


The main goal of the research group Environment and Infectious Diseases is to address the existing gaps in complex problems involving the influence of the environment in infectious diseases. This can be done by pooling interdisciplinary and multidisciplinary resources, involving national and international institutions (academic and medical centres), European networks and institutions, and Portuguese speaking countries in Africa.

The research focuses on vector borne diseases in its broadest sense, under an integrated approach that includes the entire chain of infection (agent, transmission, vectors, hosts, reservoirs, infection, immunology, diagnosis, treatment and environment), departing from the recognition of the global growing burden of vector borne diseases on Public Health systems.

The climate variation (more specifically the variation of air temperature and humidity), associated with agent-host infectious disease dynamic, and the impact of extreme weather events (heat waves, cold spells and floods), are also addressed, mainly in the development of methods and models to understand and describe the effect of climate on the disease risk.

Portugal has one of the highest prevalence of HIV infection in Europe. This, together with the long-privileged research cooperation with Portuguese speaking countries (Angola, Cape Verde, Mozambique, Sao Tome and Principe, some with the highest level of HIV infection), justifies the investment of research on the infection itself. This includes HIV-2, antiretroviral treatment and associated infections, including tuberculosis (as the most common HIV associated opportunistic infection) and cryptococcal meningitis (a major cause of death among HIV infected patients).

Group leader: Francisco José Nunes Antunes
Team members: Adriana Cunha Curado • Ana Cristina Rosado Pelerito de Araujo Goncalves • Ana Isabel de Oliveira Franco • Ana Simões • Anabela Fornelos de Vasconcelos Cavaleiro Madeira • António Duarte Teixeira Afonso Rodrigues • Armanda Góis • Artur Sérgio Gião Antunes • Catarina Isabel Lima Vieira • Cristina Maria Moreira Campos Furtado Figueiredo • Daniel Fernando da Fonseca Salvador • Emilia de Jesus da Encarnação Valadas • Fátima Isabel Falcão Amaro • Fausto José da Conceição Alexandre Pinto • Fernando Manuel Tavares Maltez • Hugo Costa Osório • Isabel Curralo Lopes de Carvalho • Maria Clara Gomes da Fonseca Pedro Bicho • Maria de Fátima Guerreiro Campante • Maria João Pereira Figueira Alves • Maria Margarida Gomes Barbosa Santos Silva Serejo • Maria Sofia Cobra Lince Núncio Soares • Raquel Filipa Pinheiro Sabino • Raquel Maria Santos Chaves • Robert Alfred Badura • Rui Sequeira • António Vaz Carneiro



1. Sabino R, Veríssimo C, Pereira AA, Antunes F (2020). Candida auris, an Agent of Hospital-Associated Outbreaks: Which Challenging Issues Do We Need to Have in Mind? Microorganisms 8(2): 181. doi:10.3390/microorganisms8020181

2. Silva R, Mavridis K, Vontas J, Rodrigues A, Osório HC (2020), Monitoring and molecular profiling of contemporary insecticide resistance status of malaria vectors in Guinea-Bissau. Acta Tropica Available online: 8 March 2020, Article 105440. doi: 10.1016/j.actatropica.2020.105440

3. Salamandane C, Fonseca F, Afonso S, Lobo ML, Antunes F, Matos O (2020). Handling of fresh vegetables: Knowledge, hygienic behavior of vendors, public health in Maputo markets, Mozambique. International Journal of Environmental Research and Public Health 17: 6302. doi: 10.3390/ijerph17176302

4. Antunes F, Veríssimo C, Pereira AA, Sabino R (2020). Candida auris: Emergência Recente de um Fungo Patogénico Multirresistente. Acta Médica Portuguesa 33(10):680-684. doi: 10.20344/amp.12419

5. Leal SV, Varela IBF, Gonçalves AAL, Monteiro DDS, Sousa CMR, Mendonça MLM, Pina AJ, Alves MJ, Osório HC (2020). Abundante and Updated Distribution of Aedes aegypti (Diptera: Culicidae) in Cabo Verde Archipelago: A Neglected Threat to Public Health. International Journal of Environmental Research and Public Health 17: 1291. doi:10.3390/ijerph17041291

6. Osório H, Rocha J, Roquette R, Guerreiro NM, Zé-Zé L, Amaro F, Silva M, Alves MJ (2020). Seasonal Dynamics and Spatial Distribution of Aedes albopictus (Diptera: Culicidae) in a Temperate Region in Europe, Southern Portugal. Int. J. Environ. Res. Public Health 17(19): 7083. doi: 10.3390/ijerph17197083

7. Zé-Zé L, Borges H, Osório H, Machado J, Gomes JP, Alves MJ (2020). Mitogenome diversity of Aedes (Stegomyia) albopictus: Detection of multiple introduction events in Portugal. PLoS Negl Trop Dis 14(9): e0008657. doi: 10.1371/journal.pntd.0008657