The Ecogenetics and human health group (RG5) studies the interactions of genetic and epigenetic host factors with health, disease, and environmental determinants during preconception and all life courses.
With these studies, we are contributing to a better understanding of the pathophysiology of the disease, focusing on its earlier detection and prevention through modulation of extrinsic environmental factors and the implementation of more personalised and effective adjuvant therapies.
Recent publications:
Ferreira I, Bicho M, Valente A. Contribution of haptoglobin phenotypic variation to the presence of hyperhomocysteinemia in type 2 diabetics with and without angiopathy. Eur J Clin Nutr. 2024 Oct 26. doi: https://doi.org/10.1038/s41430-024-01524-7
Sequeira T, Pinto R, Cardoso C, Almeida C, Aragão R, Almodovar T, Bicho M, Bicho MC, Bárbara C. HPV and Lung Cancer: A Systematic Review. Cancers (Basel). 2024 Sep 28;16(19):3325. doi: https://doi.org/10.3390/cancers16193325
Inácio Â, Aguiar L, Rodrigues B, Pires P, Ferreira J, Bilhim T, Pisco J, Bicho M, Clara Bicho M. Leiomyoma and the importance of genetic variation on genes related to the vasculature system - CβS, MTHFR, NOS3, CYBA, and ACE1. Eur J Obstet Gynecol Reprod Biol. 2024 Mar;294:65-70. doi: https://doi.org/10.1016/j.ejogrb.2024.01.009
Head: Manuel Bicho